The Global Single-use Bioreactor Market was valued at USD 3.3 Bn in 2020 and is expected to reach USD 12.4 Bn by 2027, with a growing CAGR of 21% during the forecast period.
Single-use Bioreactor Market Definition
Single-use bioreactor is also known as disposable bioreactor which is designed with a disposable bag instead of culture vessel. In this type of bioreactor, the lining of bioreactor that will be in contact with the cell culture will be plastic and this lining hold permanent structure (cuboid, cylinder or a rocker steel support). Single-use bioreactor is widely used in pharmaceutical and biotechnological companies for buffer, cell harvesting, growth media preparation, purification, and virus inactivation.
Single-use Bioreactor Market Dynamics
The driving factors for the global single-use bioreactor market include rising demand of single-use bioreactor for culture preparation which avoid the contamination & mixing of one media with other and increasing use of culture media for vaccine development. Single-use bioreactor offer set of benefits which include cost-effectiveness, negligible contamination, and these bioreactors have less maintenance cost on mechanical end. These factors contribute to the rising demand of single-use bioreactor in the ecosystem during the forecast period. Besides, availability of wide range of single-use bioreactors in terms of volume, size, dimension, and temperature control rises the demand of single-use bioreactor and help to leverage the growth of single-use bioreactor demand across the globe during the forecast period. Increase in research activities and growing collaborations of research & academic labs with companies leverage the growth of single-use bioreactor demand during the forecast period. For instance, in 2018, Novartis (Switzerland) teamed up with Wyss Institute for Biologically Inspired Engineering (US) at Harvard University and the Dana-Farber Cancer Institute (US) for research and development of implantable and injectable systems that can strengthen patient's immune response to different types of cancer. For the development of injectables, single-use bioreactors were used to carry out the reactions for single use purpose on lab-scale molecule development. Such growing demand of single-use bioreactor for research is expected to uplift the growth of single-use bioreactor demand during the forecast period.
Global Single-use Bioreactor Market Segmentation:
By Product
By Type
By Cell Type
By Molecule Type
By Applications
By Region
Company Profiles and Competitive Intelligence
The key players operating in the single-use bioreactor market are:
Based on type, stirred-tank segment is expected to contribute highest to the growth of the market during forecast period due to rise in its use in aerobic microbial culture
Based on type, single-use bioreactor market is broadly segmented into wave-induced, stirred- tank, and bubble-column. Stirred-tank held the largest market share in 2020 due to increased aerobic-culture based research activities and is expected to increase more during the forecast period owing to rising application of oxygen to carry out microbial reactions. Moreover, growing research activities and increasing use of stirred-tank single-use bioreactor for large-scale production in companies boost the growth of the segment in the single-use bioreactor demand during the forecast period. Besides, parameters such as better mixing, and oxygen transfer is expected to trigger the demand of stirred-tank bioreactors and helps to uplift the growth of single-use bioreactor during the forecast period.
Based on cell type, mammalian segment is expected to dominate the market during forecast period due to rise in research in biologics and human cells
Based on cell type, single-use bioreactor market is broadly segmented into bacterial cells, mammalian cells, and yeast cells. Mammalian segment is expected to hold the largest market share during forecast period due to increase in research on cancer cells, viral vaccines, and therapeutic proteins. Moreover, increasing use of mammalian cell using single-use bioreactor in biopharmaceutical companies based on methotrexate amplification technology or glutamine synthetase system is expected to boost the growth of segment in single-use bioreactor demand during forecast period. In addition, rising cultivation of animal cells for research purpose is further expected to stimulate the single-use bioreactor demand in the industry during the forecast period. Mammalian cell culture is extensively used in manufacturing industries which witnesses in increasing adoption of disposable or single-use bioreactor devices during the forecast period.
Based on region, North America is expected to increase more during the forecast period due to rising presence of biopharmaceutical industries in this region
Based on region, North America is expected to dominate the market during forecast period due to presence of research infrastructure and availability of strong government support in terms of funding. Moreover, rising number of key operating players in North America and increasing prevalence of chronic infectious diseases such as HIV, hepatitis and mosquito transmitted diseases are expected to leverage the growth of single-use bioreactor demand in the market during forecast period.
The report also provides an in-depth analysis of Single-use Bioreactor market dynamics such as drivers, restraints, opportunities, and challenges
Drivers
Restraints
Opportunity
Challenges
COVID-19 Impact on the Single-use Bioreactor Market Analysis
Covid-19 has positively impacted the growth of single-use bioreactor market due to rising demand for use of disposable bioreactors for vaccine development. Moreover, during pandemic, rising concern for contamination of vessel or flask by multiple use and generating need for sterile bioreactor for viral reactions are expected to leverage the growth of single-use bioreactor market during forecast period. Many biotechnological and pharmaceutical companies adopted the use of single-use bioreactors for vaccine development or clinical test phase has increased the single-use bioreactor demand and this is expected to boost the growth of single-use bioreactor during forecast period. For instance, in March 2020, Sartorious (Germany) helped CanSino Biologics Inc. (China), and Maj.Gen Che Wei’s team for the research and development of the first vaccine candidate against covid-19 to enter in clinical trials at Institute of Bioengineering at the Academy of Military Medical Sciences in China. Such collaboration for development of therapy against novel coronavirus is expected to boost the growth of single-use bioreactor during forecast period. On the contrary, there is decline in spending on global pharmaceutical R&D and fall off in biologics sale in 2020 due to sudden covid-19 outbreak is have significant impact on growth of single-use bioreactor market during the forecast period.
The report also provides an in-depth analysis of key trends in single-use bioreactor market
| Sr. No. | Trends | Impact |
| 1 | Rising application of single use bioreactor in multiple drug facilities | Positive |
| 2 | Growing advances in designing, controlling, data logging, and automation level of single use bioreactors | Positive |
The report also provides an in-depth analysis of recent news developments and investments
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