Global 3D Bioprinting Market by Component; by Application; by Material; by End Users; by Region (North America, Europe, Asia-pacific, Latin America, Middle East Africa): Global Forecasts 2021 To 2027

The Global 3D Bioprinting Market was valued at USD 1.5 Bn in 2020 and is expected to reach USD 5.1 Bn by 2027, with a growing CAGR of 19.3% during the forecast period.

3D Bioprinting Market Definition

3D bioprinting is also known as additive manufacturing that uses biomaterials such as cells, tissues, or growth factors to fabricate biomedical parts that aim to emulate the characteristics of natural tissue or organ. 3D bioprinting utilizes layer-by-layer method to deposit bioinks to fabricate tissue or organ shaped structure. 3D bioprinting is widely used in clinical applications such as organ, tissue or skin, heart fabrications, and drug research.

3D Bioprinting Market

3D Bioprinting Market Dynamics

The driving factors for the global 3D bioprinting market include rising use of 3D bioprinting in pharmaceutical & cosmetology industries and growing technological advances in the 3D bioprinting. Moreover, rising public-private funding, growing government support for research in three-dimensional bioprinting, and increasing application of 3D bioprinting in cosmetology are expected to boost the growth of 3D bioprinting demand during the forecast period. In addition, rising applications of 3D bioprinting in life sciences and in the study of cellular mechanism of organ or tissue implants and other parts of the body are expected to fuel the growth of the 3D bioprinting demand during the forecast period. Rising importance of 3D bioprinting in the pharmaceutical medicine is expected to leverage the growth of 3D bioprinting demand during the forecast period. On the contrary, the interference of the ethical challenges such as use of untested clinical paradigm based on human cells or tissues, risk of causing cancer or teratoma are expected to hamper the growth of 3D bioprinting demand in the market during the forecast period. Moreover, in the pharmaceutical industry, 3D bioprinting offers a set of advantages such as faster drug testing, cost-effectiveness, and by providing better biological relevance to humans than animal testing procedures. Such rising applications of 3D bioprinting are expected to thrive on the growth of 3D bioprinting demand across the globe.

Global 3D Bioprinting Market Segmentation:

By Component

  • 3D Bioprinters
    • Microextrusion Bioprinting
    • Magnetic 3D Bioprinting
    • Inkjet 3D Bioprinting
    • Others
  •  Bioinks
    • Synthetic Bioinks
    • Hybrid Bioinks
    • Natural Bioinks

By Applications

  • 3D Cell Culture
  • Drug Research
  • Regenerative Medicine
  • Clinical Applications
    • Skin
    • Bone & Cartilage
    • Blood Vessels
  • Others

By Materials

  • Hydrogels
  • Living Cells
  • Extracellular Matrices
  • Others

By End Users

  • Biopharmaceutical Companies
  • Research Organization & Academic Institutes
  • Hospital

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East & Africa

Company Profiles and Competitive Intelligence

The key players operating in the 3D bioprinting market are:

  • Organovo Holdings, Inc.
  • Allevi Inc.
  • Aspect Biosystems Ltd.
  • EnvisionTEC GmbH
  • Cyfuse Biomedical K.K.
  • Poietis
  • TeVido BioDevices
  • Nano3D Biosciences, Inc. 
  • ROKIT Healthcare
  • Digilab, Inc.
  • regenHU
  • GeSiM
  • Advanced Solutions Life Sciences
  • Regenovo Biotechnology Co., Ltd.
  • Advanced Biomatrix
  • 3D Biotek
  • 3D Systems
  • Avita Medical
  • Bespoke Innovations
  • Autodesk
  • EnvisionTEC
  • Cyfuse Biomedical
  • CMC Microsystems
  • United Therapeutics
  • DTM
  • Bio3D Technologies
  • Helisys Inc.
  • InSphero AG
  • BD Biosciences

Based on component, inkjet-based 3D bioprinting segment is expected to account highest market share during forecast period due to increase in fabrication of complex living tissue or organs with the help of biomaterials as bioinks

Inkjet-based bioprinting segment held the largest market in 2020 due to rising applications in medical field for tissue fabricating and is expected to increase more during forecast period. This is due to increasing healthcare infrastructure, rising investments in bioprinting equipment and growing number of surgeries. Moreover, growing applications of inkjet 3D bioprinting in drug delivery and tissue engineering is expected to boost the growth of segment in 3D bioprinting market demand. In addition to this, rising human reliability and growing demand is expected to trigger the growth of the ecosystem across the globe.

Based on applications, skin printing segment is expected to dominate the market during the forecast period due to increase in applications of 3D bioprinting in cosmetic surgeries

Based on applications, skin bioprinting in clinical applications is expected to hold the largest market share during forecast period due to increase in use of 3D bioprinting in wound healing, skin lesions or diseases, and burns. Moreover, functional human skin 3D fabrication cost less for transplantation which is expected to drive the 3D bioprinting demand in during forecast period. For instance, in September 2019, BASF Care Creation® (Ludwigshafen, Rhineland-Palatinate, Germany) and CTIBiotech (Meyzieu - Lyon, Rhône, France) joined hands to develop new 3D bioprinted skin models that would be used for the skin care applications. This technology is expected to help BASF’s scientists to enhance their 3D bioprinted skin models portfolio which would provide a platform for the skin care research and associated macrophages of the skin. Such ongoing research and development on skin 3D bioprinting is expected to boost the growth of 3D bioprinting demand during the forecast period.

Based on materials, living cells segment is expected to contribute highest to the growth of market during forecast period due to increase in application of living cells in stem cells and regenerative medicine

Based on materials, 3D bioprinting market is broadly segmented into hydrogels, living cells, and extracellular matrices. Living cells segment is expected to hold the largest market share during forecast period due to rising use of living cell as raw material in the tissue and organ fabrication. Moreover, decreasing number of organ donors is expected to leverage the growth of 3D bioprinting demand during the forecast period. In addition to this, increase in use of bio-inks of living cells for tissue generation is expected to trigger the growth of 3D bioprinting market during the forecast period.

Based on region, North America is expected to account for highest market share during forecast period due to rise in penetration to biomedical companies in this region

Based on region, North America held the largest market share in 2020 due to presence of large volume of IT infrastructure and expected to increase more during forecast period due to increasing penetration of technology in medical field. Moreover, rising prevalence of chronic cases such as organ damage or cancer, presence of huge healthcare infrastructure, growing aging population, and influx of pool of the med-tech companies is expected to boost the growth of 3D bioprinting market during the forecast period. Increasing application of 3D bioprinting in drug development and organ transplant is expected to fuel the growth of 3D bioprinting in this region in the coming years. For instance, according to the World Meter Report 2021, more than 23Mn active covid-19 cases were reported in the U.S. and more than 50 vaccine candidates are under clinical trials. Strong government support in terms of funding and grants for R&D is conditioning the pandemic condition. Due to this reason, demand for 3D bioprinting as technology for organ transplant and drug delivery is expected to thrive the growth of 3D bioprinting market during the forecast period.

The report also provides an in-depth analysis of 3D bioprinting market dynamics such as drivers, restraints, opportunities, and challenges


  • Continuous technological advancements in 3D printing industry
  • Increasing number of surgeries across the globe
  • Rising chronic diseases such as cancer, immunological diseases
  • Rising applications in personalized and regenerative medicines


  • Lack of precision related to droplet size and droplet placement in the bioprinting machine
  • Lack of skilled professionals in the industry
  • Difficulty in printing complex hollow 3D structures


  • Rising demand for regenerative medicines
  • Increase in stem cell related research


  • Poor biocompatibility
  • Socio-ethical concerns related to the use of 3D bioprinted products

COVID-19 Impact on the 3D Bioprinting Market Analysis

Covid-19 has positively impacted the growth of 3D bioprinting market due to gaining importance for the drug development during pandemic. Due to the rising burden of covid-19 cases across the globe, many 3D bioprinting companies and communities are trying to lower the global burden by providing their respective offerings and skills to ease the supply chain and governments. As the cases of covid-19 are increasing, there has been shortage of medical kits, devices, and services for healthcare professionals. Lack of availability of covid-19 testing kits, various 3D bioprinting companies offered 3D printers and related software on large scale for covid cases. For instance, Formlabs company based in Massachusetts, U.S. manufactured more than 100,000 nasal swabs for COVID-19 testing every day. Due to rising cases, the demand for 3D bioprinters has increased and 3D bioprinting industry is expected to witness exponential growth during forecast period.

The report also provides an in-depth analysis of key trends in 3D bioprinting market

Sr. No. Trends Impact
1 3D bioprinting in blood vessels, human heart, skin for wounds, and spinal cord prove to be an upcoming trend in 3D bioprinting  Positive
2 Emergence of 3D bioprinting in cancer  Positive

The report also provides an in-depth analysis of recent news developments and investments

  • In September 2021, BICO, a U.S. based company granted two patents related to the regulation of bioinks processing temperature in 3D bioprinting. The first patent is related to the temperature regulation of the printbed for precise control of gelation process for temperature sensitive materials and the second patent was granted in Sweden related to temperature controlling cartridge and dispensing nozzle. This is expected to enhance the portfolio of the company
  • In February 2021, Advanced Solutions (Louisville, KY) announced their newest patented technology named BioAssemblyBot®200. BAB200 joins BioAssemblyBot®400 (BAB400) as an automated multi-tasking bioprinter. BAB200 is expected to provide customers a benchtop to develop and execute research ideas into reality. This introduction of product is expected to pave the way for researchers and scientists to convert research ideas into reality. This launch is expected to contribute to the growth of revenue of the company.

The unique insights provided by this report also includes the following:

  • In-depth Value Chain Analysis
  • Opportunity Mapping
  • Sector Snapshot
  • Key Players Positioning Matrix
  • Regulatory Scenario
  • Strategies Adopted-Benchmarking Heat Map
  • Market Trends
  • Covid-19 Impact Analysis
  • Product Comparison
  • Pre & Post COVID 19 Impacts on 3D Bioprinting Market
  • Competitive Landscape

Frequently Asked Questions (FAQs)

The global market was valued at USD 1.5 Bn in 2020 and is anticipated to reach USD 5.1 Bn by 2027.

The global market is estimated to grow at a compound annual growth rate (CAGR) of 19.3% during forecast period.

In the base year 2020, North America accounted for largest share in the market.

Lack of trained professionals and inflated cost of device for repetitive use restraint the growth of market.

As per expert opinions, increasing incidences of chronic diseases, growing demand for 3D bioprinting for organ or tissue fabrication, and government spending on healthcare will drive the growth of market.

Few key players include, but not limit up to: Organovo Holdings, Inc., CELLINK, Allevi Inc., Aspect Biosystems Ltd., EnvisionTEC GmbH, Cyfuse Biomedical K.K., Poietis, TeVido BioDevices, Nano3D Biosciences, Inc., and ROKIT Healthcare.

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  1.  Introduction
    1. Product Outline
    2. What is 3D Bioprinting?
    3. Analysis of 3D Bioprinting Market
    4. Covid -19 Impact
    5. Market Dynamics
      1. Drivers
      2. Restraints
      3. Opportunities
      4. Threats
    6. Technology Overview
  2. Regulatory Landscape for 3D Bioprinting Market
    1. Regulations and Standards
  3. 3D Bioprinting Market by Component
    1. 3D Bioprinters
      1. Microextrusion Bioprinting
      2. Magnetic 3D Printing
      3. Inkjet 3D Bioprinting
      4. Others
    2. Bioinks
      1. Synthetic Bioinks
      2. Hybrid Bioinks
      3. Natural Bioinks
  4. 3D Bioprinting Market by Applications
    1. 3D Cell Culture
    2.  Drug Research
    3. Regenerative Medicine
    4. Clinical Applications
      1. Skin
      2. Bone & Cartilage
      3. Blood Vessels
    5. Others
  5. 3D Bioprinting Market by Materials
    1. Hydrogels
    2. Living Cells
    3. Extracellular Matrices
    4. Others
  6. 3D Bioprinting Market by End User
    1. Biopharmaceutical Companies
    2. Research Organization & Academic Institutes
    3. Hospital
  7. Regional Analysis
    1. North America
      1. US
      2. Canada
    2. Europe
      1. Germany
      2. UK
      3. France 
      4. Spain
      5. Italy
      6. Rest Of Europe
    3. Asia Pacific
      1. China
      2. India
      3. Japan
      4. Australia
      5. Rest Of Asia Pacific
    4. Latin America
      1. Brazil
      2. Mexico
      3. Rest of Latin America
    5. Middle East Africa (MEA)
      1. GCC
      2. Rest of MEA
  8. Key Strategic Insights
    1. New Applications
    2. Emerging Technologies
    3. Opportunity Mapping
    4. Critical Success Factors
    5. Environmental Impact and Sustainability Issues
    6.  Customer Preferences
  9. Key Market Trends / Recent Developments
  10. Competitive Scenario
    1. Mergers and Acquisitions
    2. Investments
    3. Joint Ventures
    4. New Product launches
    5. Presence of Players by Geographies
  11. Key global players
    1. Organovo Holdings, Inc.
    2. CELLINK
    3. Allevi Inc.
    4. Aspect Biosystems Ltd.
    5. EnvisionTEC GmbH
    6. Cyfuse Biomedical K.K.
    7. Poietis
    8. TeVido BioDevices
    9. Nano3D Biosciences, Inc.
    10. ROKIT Healthcare
    11. Digilab, Inc.
    12. regenHU
    13. GeSiM
    14. Advanced Solutions Life Sciences
    15. Regenovo Biotechnology Co., Ltd.
    16. Others

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