3D Cell Culture Market by Product (Scaffold-Based Platforms, Scaffold-Free Platforms, Bioreactors), by Application (Cancer, Drug Discovery, Stem Cell Research, Others), by End User (Research Laboratories & Institutes, Biotechnology & Pharmaceutical Companies, Hospitals and Diagnostic Centers) by Region (North America, Europe, Asia-Pacific, Rest of the World): Global Forecasts 2017 To 2027

The Global 3D Cell Culture Market Size was valued at US$ 1,605.4 Mn in 2020 is expected to reach US$ 3,323.3 Mn by 2027, with a growing CAGR of 11.2% during the forecast period (2021-2027).

3D cell culture is a process of growing cells in an artificially created or cultured environment which involve interacting with surrounding extracellular framework in three dimensions. In 3D cell culture, cells are allowed to grow in all directions such as cells grown in in-vivo. In 3D cell cultures, cells can be grown with or without scaffold support. Generally, 3D cells are grown in small capsules, bioreactors or in 3D cell colonies.  This is used to study multicellular structures, such as acinar structure in healthy or cancerous breast tissue models. This model can be used to study or evaluate cellular response of pharmaceutical active moiety on cells and body.

3D Cell Culture Market

3D cell culture is used to provide more physiological data and information for in-vivo tests. This is more widely used to study the different heavy drug molecules on cells of body which include, cancerous drugs, drugs used in genetic dispositions etc.The growth of 3D Cell Culture market is driven by various factors such as increase in development of research techniques, animal testing and rise in research infrastructure.  Further, rising focus on personalized medicines, growing government funding and initiatives in R&D sector and increase in prevalence of diseases across the globe give rise to the growth of 3D cell culture market.

For instance, in December 2020, eNUVIO, Canadian company launched reusable microplate for 3D cell culture known as EB-plate. The aim towards this invention was to decrease the use of single use plate and promote zero-waste movement in research laboratories. This creates opportunity for development of more innovative and sensitive culture techniques and procedure for 3D cell culture.

3D Cell Culture Market Segmentation:

By Product

  • Scaffold-Based Platforms
  • Scaffold-Free Platforms
  • Bioreactors

By Application

  • Cancer
  •  Drug Discovery
  • Stem Cell Research
  • Others

By End User

  • Research Laboratories & Institutes
  • Biotechnology & Pharmaceutical Companies
  • Hospitals and Diagnostic Centers

By Region

  • North America
  •  Europe
  •  Asia-Pacific
  •  Rest of the World

Based on product, scaffold-based 3D cell culture Market segment account the highest market share in 2020 and expected to grow more during forecast period.

Based on products, 3D cell culture market is segmented into Scaffold-Based Platforms, Scaffold-Free Platforms, and Bioreactors. Scaffold-based platform in 3D Cell Culture market held maximum market share in 2020 due to various advantages provided by scaffold are, it provides structural rigidity, strong support and have maximum attachment points. It provides a proper surface for the cell growth in three-dimension, scaffold-based platform is used in drug discovery and cell expansion. Moreover, it provides ease of imaging and have easy protocols for study. This platform is widely used in research of large drug molecules such as drug moieties used in cancer etc. Mechanical and biochemical properties can be easily modified according to the requirements and this create niche for scaffold-based 3D cell culture in the market. However, this platform absorbs test compounds and limits the analysis at the end.

Based on application, cancer segment is anticipated to grow highest during forecast period due to increase in prevalence of cancer within population.

Based on applications, 3D cell culture market is segmented into Cancer, Drug Discovery, Stem Cell Research and Others. Cancer segments held maximum market share in 2020 and is expected to witness lucrative profit during the forecast period. This is due to increase in prevalence of cancer and research associated with cancer treatment drives the growth of this segment in 3D cell culture market. In cancer application, 3D cell culture provide ease of cell altering proliferation, morphology and analyze drug response. Moreover, it also helps in experimental manipulation in gene expression and study of cell behaviour. This help in preclinical studies to analyze drug molecule and provide overview of cell reaction.

Based on end user, pharmaceutical and biotechnological companies accounted the highest market share in 2020 and is expected to increase more during forecast period due to rise in facilities and funding for research and development.

Based on end user, 3D cell culture market is segmented into Research Laboratories & Institutes, Biotechnology & Pharmaceutical Companies, and Hospital and Diagnostic Centers. Pharmaceutical & biotechnological segment accounted the highest market share in 2020. This is due to the increase in government funding in research and development practice, presence for large number of industries, growing demand for more sensitive model for research, rising preference for alternative testing models over animals that drives the growth of 3D cell culture market in this segment. 

Moreover, academic institutes hold second position in growth of market. This is due to increasing collaborations of companies to academic, research and clinical laboratories, further rise in demand for 3D cell culture in drug discovery and in healthcare. Now-a-days many academic institutes are focussing on research and development practices towards 3D culture models for novel discoveries such as microfluidic technology which would provide great potential for in vivo tissue based application and emerging invention in organ-on-a-chip system. The surge of research activities in academic institutes drives the growth of market in this segment.

Based on geographical region, North America dominated the 3D cell culture market in 2020 and expected to have same dominance during forecast period due to availability of research-based facilities & infrastructure and strong government support in North America.

Based on region, 3D cell culture market is segmented into various regions across the globe such as North America, Asia-Pacific, Europe and rest of the world. Amongst them, North America has dominated 3D cell culture market in 2020 due to increasing practices of research and development infrastructure, rise in healthcare companies, increasing in government funding. Moreover, the rise in development in novel drug, increasing demand for personalized medicine, surge in incidence of cancer have impacted the growth of 3D cell culture market in this region.

However, Europe is expected to witness  a tremendous growth with the highest CAGR during forecast period. This is due to the recent commercialization of microfluids-based products and rising number of key players in 3D cell culture market drives the growth in this region.

Company Profiles and Competitive Intelligence

The key players operating in the market are:

  • Thermo Fisher Scientific
  •  Corning Incorporated
  • Merck KGaA
  • Lonza AG
  • REPROCELL Incorporated
  • TissUse
  • InSphero
  • Synthecon
  • 3D Biotek
  • CN Bio
  • Hamilton Company
  • Emulate
  • Hµrel Corporation
  • QGel SA
  • SynVivo
  • Advanced BioMatrix
  • Greiner Bio-One International
  • PromoCell

The report also provides an in-depth analysis of 3D cell culture market dynamics such as drivers, restraints opportunities, and challenges


  • Rise in government spending in R&D
  • Increase in product approvals and launches
  • Rise in prevalence of infectious diseases and cancer
  • Increase in demand for personalised medicine
  • Increase in technological advances in healthcare


  • Lack of consistency in products such as scaffolds and extracellular matrices


  • Growing concern in emergence of microfluid-based 3D cell culture and organ transplantation with help of generative medicines provides opportunity for growth of market
  • Rise in number of players and companies in 3D cell culture market
  • Increase in mergers and acquisitions and collaboration with academic institute creates growth opportunity

COVID-19 Impact on the 3D Cell Culture Market Analysis

Covid-19 has highly affected the industries in terms of growth, economy, health and mental wellbeing of every individual. In this challenging situation, every industry is trying to give best services in terms of quality and safety.  Due to restrictions on movement and closer of many manufacturing units, there has been a sudden decrease in supply of raw materials and components need for development of cell culture. Moreover, disruption in supply chain, export and import activities has been affected by pandemic.

Due to lockdown and social distancing guidelines, there is a decrease in number of human resources and man power for production process. This has negatively impacted the growth of 3D cell culture market. However, there has been increase in research and development activities for the development of vaccines and treatment against covid-19. This lifts the growth and demand for cell culture in the 3D cell culture market.

Further, research associated with regenerative medicine and stem cells have proved to be effective in treating Covid-19, however, this creates opportunity for the players and normalized the impact caused by covid-19 outbreak in the 3D cell culture industry. The overall covid-19 impact on 3D cell culture industry remained normal and provided opportunity for players in the market.

The report also provides in-depth analysis of key trends in 3D cell culture market

  • Surge in incidence of cancer across the world has led the government to increase funding for research and development in field of cancer and infectious diseases, which reflects as a positive impact on growth of 3D Cell Culture Market
  • Increase in government initiatives, development in innovative techniques and demand for personalised medicine drives the growth of 3D cell culture market growth.

The report also provides in-depth analysis of recent news developments and investments

  • In June 2020, Corning, Inc introduced Corning X-Series cell processing platform for gene therapy application. This platform proves to be sterile, efficient, fast, and has automated processing.
  • In January 2019, Visikol launched OpenLiver 3D Cell Culture Models to expand their service offering and to accelerate drug discovery

The unique insights provided by this report also includes the following:

  • In-depth Value Chain Analysis
  • Opportunity Mapping
  • Sector Snapshot
  • Key Players Positioning Matrix
  • Regulatory Scenario
  • Strategies Adopted-Benchmarking Heat Map
  • Market Trends
  • Covid-19 Impact Analysis
  • Product Comparison
  • Pre & Post COVID 19 Impacts on 3D Cell Culture Market
  • Competitive Landscape

Frequently Asked Questions (FAQs)

The global 3D cell culture market was valued at US$ 1,605.4 Mn in 2020 and is anticipated to reach US$ 3,323.3 Mn by 2027

The 3D cell culture market is estimated to grow at a compound annual growth rate (CAGR) of 11.2% during 2021-2027

In the base year 2020, North America accounted for about 35% share in the 3D cell culture market

Stringent regulatory policies for product approvals and lack of consistency in products restraint the growth of global 3D cell culture market.

Few key players include, but not limit up to: Thermo Fisher Scientific, H amilton Company, Corning Incorporated, Lonza AG, REPROCELL Incorporated, TissUse, InSphero, Synthecon, Merck KGaA , 3D Biotek, CN Bio and and MIMETAS

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    1. Product Outline
    2. What is 3D Cell Culture
    3. Analysis of 3D Cell Culture
    4. Covid -19 Impact
    5. Market Dynamics
      1. Drivers
      2. Restraints
      3. Opportunities
      4. Threats
    6. Technology Overview
  2. Regulatory Landscape for 3D Cell Culture
    1. Regulations and Standards
  3. 3D Cell Culture Market by Product
    1. Scaffold-Based Platforms
    2. Scaffold-Free Platforms
    3. Bioreactors
  4. 3D Cell Culture Market by Application
    1. Cancer
    2. Drug Discovery
    3. Stem Cell Research
    4. Others
  5. 3D Cell Culture Market by End User
    1. Research Laboratories & Institutes
    2. Biotechnology & Pharmaceutical Companies
    3. Hospitals and Diagnostic Centers
  6. Regional Analysis
    1. North America
      1. US
      2. Canada
    2. Europe
      1. Germany
      2. UK
      3. France 
      4. Spain
      5. Italy
      6. Rest Of Europe
    3. Asia Pacific
      1. China
      2. India
      3. Japan
      4. Australia
      5. Rest Of Asia Pacific
    4. Rest of the World
  7. Key Strategic Insights
  8. New Raw Material Sources
    1. New Applications
    2. Emerging Technologies
    3. Opportunity Mapping
    4. Critical Success Factors
    5. Consumer Preferences
  9. Key Market Trends / Recent Developments
  10. Competitive Scenario
    1. Mergers and Acquisitions
    2. Investments
    3. Joint Ventures
    4. New Product Launches
    5. Ranking of Key Players
    1. Thermo Fisher Scientific
    2. Corning Incorporated
    3. Merck KGaA
    4. Lonza AG
    5. REPROCELL Incorporated
    6. TissUse
    7. InSphero
    8. Synthecon
    9. 3D Biotek
    10. CN Bio
    11. Hamilton Company
    12. MIMETAS

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